这个肯定有的了。Mi R-206 Attenuates Denervation-Induced Skeletal Muscle Atrophy in Rats Through Regulation of Satellite Cell Differentiation via TGF-b1, Smad3, and HDAC4 Signaling。这篇文献做的大鼠的。首先造模之后腓肠肌局部注射mir206。见附件。还有一个是做的猪的sirna的。Coronary Microembolization InducesCardiomyocyte Apoptosis in Swineby Activating the LOX-1-DependentMitochondrial Pathway andCaspase-8-Dependent Pathway当然了,动物用的越大,也越烧钱啊。一般文献上都是做小鼠的。